7144120
JMJD1C Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
JMJD1C
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
RP11-10C13.2, TRIP8; TR-interacting protein 8; TRIP-8; jumonji domain-containing protein 1C; probable JmjC domain-containing histone demethylation protein 2C; thyroid hormone receptor interactor 8; thyroid receptor interacting protein 8; thyroid receptor-interacting protein 8
Gene Symbols
JMJD1C
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q15652
Gene ID (Entrez)
221037
Immunogen
Between 150 and 200
Primary or Secondary
Primary
Content And Storage
4° C
Gene
JMJD1C
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Bovine, Panda, Orangutan, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Small-eared galago The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism
- Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation
- JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors
- The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer
- At least three isoforms of JMJD1C are known to exist.