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7144241

SF3b145/SAP145 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

SF3b145/SAP145

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

Splicing factor 3B subunit 2, Pre-mRNA-splicing factor SF3b 145 kDa subunit, SF3b145, SF3b150, Spliceosome-associated protein 145, SAP 145, SF3B2, SAP145

Immunogen

Between 775 and 825

Primary or Secondary

Primary

Content And Storage

4° C

Gene

SF3B2

Applications

Immunofluorescence, Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

Q13435

Gene ID (Entrez)

10992, 319322

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Horse, Rabbit, Pig, Panda, Monkey, Gorilla, Chimpanzee, White-tufted-ear marmos Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA
  • Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA
  • May also be involved in the assembly of the 'E' complex
  • Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.