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7144313

SSB1 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

SSB1

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

SOSS complex subunit B1, Nucleic acid-binding protein 2, Oligonucleotide/oligosaccharide-binding fold-containing protein 2B, Sensor of single-strand DNA complex subunit B1, Sensor of ssDNA subunit B1, SOSS-B1, Single-stranded DNA-binding protein 1, hSSB1, NABP2, OBFC2B, SSB1

Immunogen

Between 161 and 211

Primary or Secondary

Primary

Content And Storage

4° C

Gene

NABP2

Applications

Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

Q8R2Y9, Q9BQ15

Gene ID (Entrez)

69917, 79035

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda, Orangutan, Monkey, Gorilla Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint
  • In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines
  • The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintece of genomic stability
  • Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.