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7162581

Carbonic Anhydrase I Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Carbonic Anhydrase I

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse

Gene Alias

AW555628, CA I, CA1, ca1 {ECO:0000250, CAB, CA-I, CA-I {ECO:0000250, Car1, Car-1, Carbonate dehydratase I, carbonate dehydratase I {ECO:0000250, carbonic anhydrase 1, carbonic anhydrase 1 {ECO:0000250, Carbonic anhydrase B, carbonic anhydrase I, carbonic anhydrase I {ECO:0000250, epididymis secretory protein Li 11, HEL-S-11, UniProtKB:P00915}

Gene Symbols

CA1, Car1

Primary or Secondary

Primary

Product Type

Antibody

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Gene Accession No.

P00915, P13634

Gene ID (Entrez)

12346, 759

Isotype

IgG

Content And Storage

-20°C or -80°C if preferred

Gene

CA1

Description

  • Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide
  • They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid
  • They show extensive diversity in tissue distribution and in their subcellular localization
  • CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes
  • Variants of this gene have been described in some populations
  • Multiple alternatively spliced variants, encoding the same protein, have been identified
  • Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.