7181439
Invitrogen™ LanthaScreen™ Tb-anti-PRAS40 [pThr246] Antibody Kit
A part of the PI3K/AKT Pathway, PRAS40 (Proline-rich AKT substrate, 40 kDa) is a cytosolic protein that is phosphorylated at position Thr246 by AKT directly upon stimulation of the pathway.
Manufacturer: Fischer Scientific
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Conjugate
Tb (Terbium)/Lanthanide Chelates
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Description
- A part of the PI3K/AKT Pathway, PRAS40 (Proline-rich AKT substrate, 40 kDa) is a cytosolic protein that is phosphorylated at position Thr246 by AKT directly upon stimulation of the pathway
- PRAS40 has been shown to bind to the mTORC1 complex and inhibit downstream signaling (i.e., phosphorylation of 4E-BP1 or p70S6K)
- For use in combination with the LanthaScreen™ PRAS40 HEK293E cell line (K1528) to evaluate inhibitors in medium to high throughput screening applications.