7188373

NKX2.5 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

NKX2.5

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P52952

Gene ID (Entrez)

1482

Immunogen

This NkX2.5 antibody was raised against a peptide within the N-terminal region of human NkX2.5.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

Nkx2-5

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias

Cardiac-specific homeobox; cardiac-specific homeobox 1; CHNG5; CSX; CSX1; Drosophila NK2 transcription factor related, locus 5; FLJ52202; FLJ97166; FLJ97195; FLJ97197; FLJ99536; HLHS2; Homeobox protein CSX; Homeobox protein NK-2 homolog E; homeobox protein NKX 2-5; Homeobox protein Nkx-2.5; NK2 homeobox 5; NK2 transcription factor related locus 5; NK2 transcription factor related, locus 5; NKX 2-5; NKX2.5; Nkx-2.5; Nkx-25; Nkx2-5; Nkx2e; NKX4-1; rNKx-2.5; tinman; tinman paralog; VSD3

Gene Symbols

Nkx2-5

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • This gene encodes a homeobox-containing transcription factor
  • This transcription factor functions in heart formation and development
  • Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases
  • Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition
  • Alternative splicing results in multiple transcript variants.