PITX2 Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PITX2
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q99697
Gene ID (Entrez)
5308
Immunogen
This PITX2 antibody was raised against a peptide within the N-terminal region of human PITX2.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
PITX2
Concentration
Lot-Specific
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
9430085M16Rik; all1-responsive gene 1; ALL1-responsive protein ARP1; ARP1; BOS_6374; Brx1; BRX1 homeoprotein; Brx1b; Homeobox protein PITX2; homeodomain transcription factor 2; IDG2; IGDS; IGDS2; IHG2; IRID2; Munc30; Orthodenticle-like homeobox 2; Otlx2; paired like homeodomain 2; paired-like homeodomain 1; paired-like homeodomain 2; paired-like homeodomain transcription factor 1; Paired-like homeodomain transcription factor 2; Paired-like homeodomain transcription factor Munc 30; Pituitary homeobox 2; PITX1; PITX2; Pitx-2; Pitx2c; Ptx2; RGS; RIEG; RIEG bicoid-related homeobox transcription factor; rieg bicoid-related homeobox transcription factor 1; RIEG1; rPtx2; RS; S a 1 glycoprotein; S a1glycoprotein; S alpha 1 glycoprotein; S a 1 glycoprotein; S a1glycoprotein; Solurshin
Gene Symbols
PITX2
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- Pilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins
- This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression
- It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin
- Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly
- A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.