7188584

Histone H3K9me3 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Histone H3K9me3

Applications

ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, ELISA, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P68431, P84243, Q6NXT2, Q71DI3

Gene ID (Entrez)

126961, 3020, 3021, 333932, 440093, 8350, 8357, 8358, 8968

Immunogen

This Histone H3 trimethyl Lys9 antibody was raised against a peptide including trimethyl-lysine 9 of histone H3.

Primary or Secondary

Primary

Product Type

Antibody

Concentration

Conc. Not Determined

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias

H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3B.1; H3 histone, family 3C; H3 K9; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3b; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3C10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3F3B; h3f3b.1; H3F3C; h3f3d; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3K9; H3Lys9me3; Hist1; HIST1H3A; Hist1h3b; Hist1h3c; Hist1h3d; HIST1H3E; HIST1H3F; HIST1H3G; Hist1h3h; Hist1h3i; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; histone 1, H3a

Gene Symbols

H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7

Isotype

IgG

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

H3-3A

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Description

  • Description Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells
  • H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome
  • Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability
  • Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors
  • The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes
  • These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.