7188680

Histone H2BK15ac Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Histone H2BK15ac

Applications

Dot Blot, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

O60814, P23527, P62807, Q16778, Q5QNW6, Q6DN03, Q6DRA6, Q99877

Gene ID (Entrez)

337873, 337874, 440689, 8339, 8341, 8346, 8347, 8348, 8349, 85236

Immunogen

This antibody was raised against a peptide including acetyl-lysine 15 of human histone H2B.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

H2BC12

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias

2610022J01Rik; Acetyl-Histone H2; Acetyl-Histone H2B K15; Acetyl-Histone H2B Lys15; AV127319; dJ193B12.2; dJ221C16.3; dJ221C16.8; GL105; H2B; H2b 613; H2B GL105; H2B histone family, member A; H2B histone family, member D; H2B histone family, member K; H2B histone family, member L; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member S; H2B histone family, member T; H2B K; H2B.1; H2B.1A; H2B.2; H2B/a; H2B/d; H2B/g; H2B/h; H2B/I; H2B/k; H2B/l; H2B/n; H2B/o; H2B/q; H2B/s; H2B/t; H2b-613; H2BC10; H2BC4; H2BC6; H2BC7; H2bc8; H2BFA; H2BFAiii; H2BFD; H2BFG; H2BFH; H2BFK; H2BFL; H2BFN; H2BFO; H2BFQ; H2bfs; H2BFT; H2BGL105; H2BK; H2BK12ac; H2BK15ac; H2BK5ac; H2BLys15ac; H2BQ; H2BS14; H2BS14p; HIRA-interacting protein 1; HIRIP1; Hist1h2ba; Hist1h2bc; Hist1h2be; HIST1H2BF; HIST1H2BG; HIST1H2BI; Hist1h2bk; HIST1H2BN; HIST1H2BO; HIST1H3I; HIST2H2BC; HIST2H2BD; HIST2H2BE; HIST2H2BF; histone 1, H2ba; histone 1, H2bc; histone 1, H2bg; histone 1, H2bi; histone 1, H2bk; histone 1, H2bn; histone 1, H2bo; histone 2, H2be; Histone 2B; histone cluster 1, H2ba; histone cluster 1, H2bc; histone cluster 1, H2bg; histone cluster 1, H2bi; histone cluster 1, H2bk; histone cluster 1, H2bn; histone cluster 1, H2bo; histone cluster 2, H2bc (pseudogene); histone cluster 2, H2bd (pseudogene); histone cluster 2, H2be; histone cluster 2, H2bf; histone family member; histone H2B; Histone H2B type 1-A; Histone H2B type 1-C/E/F/G/I; Histone H2B type 1-C/E/G; Histone H2B type 1-K; Histone H2B type 1-N; Histone H2B type 1-O; Histone H2B type 2-E; Histone H2B type 2-F; Histone H2B, testis; Histone H2B.1 A; Histone H2B.2; Histone H2B.a; Histone H2B.d; Histone H2B.g; Histone H2B.h; Histone H2B.I; Histone H2B.k; Histone H2B.l; Histone H2B.n; Histone H2B.q; Histone H2B-GL105; MGC125414; MGC125415; MGC125416; MGC9388; R74621; RP1-193B12.10; T25626; testis-specific histone 2b; Testis-specific histone H2B; Th2b

Gene Symbols

H2BC10, H2BC12, H2BC15, H2BC17, H2BC18, H2BC19P, H2BC20P, H2BC21, H2BC4, H2BC8

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes
  • Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4)
  • The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template
  • Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability
  • H2B has a broad antibacterial activity.