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7188839

EED Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™

Mouse Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

EED

Applications

ChIP sequencing (ChIP-seq), ELISA

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

O75530

Gene ID (Entrez)

8726

Immunogen

This EED antibody was raised against full-length recombinant human EED protein.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

EED

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

200mM HEPES, 50mM sodium acetate with 100mM NaCl, 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias

EED; embryonic ectoderm development; Embryonic ectoderm development protein; ENSMUSG00000039373; hEED; l(7)5Rn; l7Rn5; lethal, Chr 7, Rinchik 5; lusk; Polycomb protein EED; WAIT1; WAIT-1; WD protein associating with integrin cytoplasmic tails 1

Gene Symbols

EED

Isotype

IgG2a

Purification Method

Metal-chelate chromatography

Product Type

Antibody

Description

  • The EED protein (WAIT-1 or WD protein associated with integrin cytoplasmic tails-1), also called embryonic ectoderm development, is a member of the superfamily of WD-40 repeat proteins and widely conserved polycomb group (PcG) family of proteins
  • The polycomb group (PcG) is a large and evolutionarily conserved set of genes whose products act in multimeric complexes to modify histones, which are then thought to cause stable and heritable states of transcriptional repression
  • EED shuttles between the nucleus and the plasma membrane and can interact with the cytoplasmic tail of integrin Beta-7 subunit
  • EED exerted an antiviral activity at the late stage of HIV-1 replication.