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7188847

PAX5 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

PAX5

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q02548

Gene ID (Entrez)

5079

Immunogen

This antibody was raised against a peptide within the N-terminal region of human PAX5.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

PAX5

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias

ALL3; B-cell lineage specific activator; B-cell-specific transcription factor; BSAP; EBB-1; KLP; paired box 5; paired box gene 5; paired box homeotic gene 5; Paired box protein Pax-5; paired domain gene 5; PAX5; Pax-5; Pax5 variant 1; Pax5 variant 2; RGD1565236; transcription factor PAX 5

Gene Symbols

PAX5

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Description

  • Description PAX5 is a member of the paired box (PAX) family of transcription factors
  • The PAX proteins are important regulators in early development and alterations in the expression of their genes are thought to contribute to neoplastic transformation
  • PAX5 is the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages, of B-cell differentiation
  • Its expression has also been detected in developing CNS and testis, therefore, PAX5 may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis
  • Mutations in the gene can result in leukemia, acute lymphoblastic 3.