Ago3 Monoclonal Antibody (4B1-F6), Active Motif™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Ago3
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias
AGO3; argonaute 3; argonaute 3, RISC catalytic component; Argonaute RISC catalytic component 3; argonaute RISC catalytic subunit 3; Argonaute3; AW048688; BOS_3617; C130014L07Rik; eIF2C 3; eIF-2C 3; EIF2C1; EIF2C3; Eukaryotic translation initiation factor 2C 3; eukaryotic translation initiation factor 2C, 1; eukaryotic translation initiation factor 2C, 3; hAgo3; mAgo3; Piwi/argonaute family protein meIF2C3; Protein argonaute-3
Gene Symbols
AGO3
Isotype
IgG2a
Purification Method
Protein G
Product Type
Antibody
Clone
4B1-F6
Applications
ChIP Assay, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q9H9G7
Gene ID (Entrez)
192669
Immunogen
This Ago3 (Argonaute 3) antibody was raised against a recombinant protein corresponding to amino acids 1-175 of human Ago3.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
AGO3
Related Products
Description
- AGO3 (protein argonaute-3) is required to RNA-mediated gene silencing (RNAi)
- It binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them
- AGO3 is proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.