Home Products Antibodies Primary Antibodies 7188899
7188899

Phospho-MeCP2 (Ser80) Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-MeCP2 (Ser80)

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Rat

Gene Accession No.

P51608, Q00566

Gene ID (Entrez)

29386, 4204

Immunogen

This MeCP2 phospho Ser80 antibody was raised against a peptide containing phospho Ser80 of mouse MeCP2.

Primary or Secondary

Primary

Product Type

Antibody

Concentration

Conc. Not Determined

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias

1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; Methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10

Gene Symbols

Mecp2

Isotype

IgG

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

Mecp2

Description

  • MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain
  • MECP2 is capable of binding specifically to methylated DNA
  • DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development
  • MECP2 can also repress transcription from methylated gene promoters
  • In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation
  • MECP2 is dispensible in stem cells, but is essential for embryonic development
  • MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.