7190564
IL-17E Monoclonal Antibody (11K8B1), Rockland™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
IL-17E
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
IL17E; IL-17E; IL25; IL-25; ILN; Interleukin; interleukin 17E; interleukin 25; Interleukin-17E; Interleukin-25; RGD1561632; UNQ3120/PRO10272
Gene Symbols
IL25
Isotype
IgG1
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
IL25
Clone
11K8B1
Applications
ELISA, Flow Cytometry, Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q9H293
Gene ID (Entrez)
64806
Immunogen
Anti-IL-17E (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17E produced in E.coli followed by hybridoma development.
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This antibody is specific for human IL-17E protein
- A BLAST analysis was used to suggest cross-reactivity with IL-17E from human sources based on 100% homology with the immunizing sequence
- Cross-reactivity with IL-17E from other sources has not been determined
- Interleukin 25 (IL-25) is a member of the IL-17 family and is identified as a proinflammatory cytokine which is produced by Th17 effector cells thus enabling the Th17 subset to initiate or maintain the autoimmune process in diseases such as Rheumatoid Arthritis
- IL-25 also induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8
- IL-25 itself is activated through IL-23, IL-5, and TGF-beta.