ABCB8 Polyclonal Antibody, Rockland™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
ABCB8
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q9NUT2
Gene ID (Entrez)
11194
Immunogen
ABCB8 was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a internal portion of human ABCB8.
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
ABCB8
Concentration
80 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
4833412N02Rik; AA409895; ABC transporter 8; Abcb8; ATP binding cassette subfamily B member 8; ATP-binding cassette sub-family B member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8; ATP-binding cassette, sub-family B (MDR/TAP), member 8; ATP-binding cassette, sub-family B, member 8; BOS_4761; EST328128; hypothetical protein LOC548340; MABC1; M-ABC1; mitochondrial ABC protein; Mitochondrial ATP-binding cassette 1; zgc:113037
Gene Symbols
ABCB8
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- A BLAST analysis was used to suggest cross-reactivity with ABCB8 from human, mouse, and rat based on a 100% homology with the immunizing sequence
- Reactivity against homologues from other sources is not known
- The antibody detects ABCB8 in cell lysates
- This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane
- The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria
- Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol
- Alternative splicing results in multiple transcript variants.