7190911

PAX6 Monoclonal Antibody (7H10.D3.D4.G5), Rockland™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

PAX6

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias

1500038E17Rik; AEY11; AN; AN2; Aniridia; Aniridia type II protein; D11S812E; Dey; Dickie's small eye; FVH1; Gsfaey11; Keratitis; MGC17209; MGDA; Oculorhombin; paired box 6; paired box gene 6; Paired Box Gene-6; paired box homeotic gene 6; paired box homeotic gene-6; Paired box protein Pax-6; Pax6; Pax-6; Sey; small eye; WAGR

Gene Symbols

PAX6

Isotype

IgG1 κ

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

PAX6

Clone

7H10.D3.D4.G5

Applications

ELISA, Immunofluorescence, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P26367

Gene ID (Entrez)

5080

Immunogen

PAX6 protein A purified antibody was prepared in mice by repeated immunizations with a recombinant protein corresponding to human PAX6 protein.

Primary or Secondary

Primary

Product Type

Antibody

Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • Cross-reactivity with PAX6 from other sources has not been determined
  • This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd
  • In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain
  • Both domains are known to bind DNA, and function as regulators of gene transcription
  • This gene is expressed in the developing nervous system, and in developing eyes
  • Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly
  • Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene.