AKT3 Monoclonal Antibody (25F6.F6.D8), Rockland™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
AKT3
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
AI851531; AKT serine/threonine kinase 3; AKT3; AKT3 kinase; akt3a; D930002M15Rik; DKFZP434N0250; MPPH; MPPH2; Nmf350; PKB gamma; PKBG; PKB-GAMMA; PRKBG; Protein kinase Akt-3; Protein kinase B gamma; protein kinase B, gamma; RAC-gamma; RAC-gamma serine/threonine protein kinase; RAC-gamma serine/threonine-protein kinase; RAC-PK-gamma; si:ch211-221n23.2; STK-2; thymoma viral proto-oncogene 3; v-akt murine thymoma viral oncogene 3; v-akt murine thymoma viral oncogene homolog 3; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); v-akt murine thymoma viral oncogene homolog 3a; v-akt murine thymoma viral oncogene-like 3
Gene Symbols
AKT3
Isotype
IgG1 κ
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
AKT3
Clone
25F6.F6.D8
Applications
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q9Y243
Gene ID (Entrez)
10000
Immunogen
Anti-AKT3 Antibody was produced in mice by repeated immunizations with a synthetic peptide corresponding to internal residues of human AKT3 protein.
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- Anti-AKT3 antibody is directed against human AKT3
- The antibody detects both unphosphorylated and phosphorylated forms of the protein
- Cross reactivity with AKT3 from other species has not been determined, however, the sequence of the immunogen shows 100% identity to human, mouse, and rat, therefore, cross reactivity is expected
- Cross-reactivity with AKT2 and AKT has not been determined
- The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family
- AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors
- They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake
- This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1)
- Alternatively splice transcript variants encoding distinct isoforms have been described.