Carbonic Anhydrase I Polyclonal Antibody, HRP, Rockland™
Goat Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Carbonic Anhydrase I
Applications
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate
HRP
Host Species
Goat
Target Species
Human
Gene Accession No.
P00915
Gene ID (Entrez)
759
Immunogen
Carbonic Anhydrase I [Human Erythrocytes ]
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene
CA1
Concentration
1 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias
AW555628; CA I; CA1; ca1 {ECO:0000250; CAB; CA-I; CA-I {ECO:0000250; Car1; Car-1; Carbonate dehydratase I; carbonate dehydratase I {ECO:0000250; Carbonic anhydrase 1; carbonic anhydrase 1 {ECO:0000250; Carbonic anhydrase B; Carbonic anhydrase I; carbonic anhydrase I {ECO:0000250; epididymis secretory protein Li 11; HEL-S-11; UniProtKB:P00915}
Gene Symbols
CA1
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at 4°C prior to restoration
- For extended storage aliquot contents and freeze at -20°C or below
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- Carbonic Anhydrase I is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above
- Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti-Goat Serum as well as purified and partially purified Carbonic Anhydrase I [Human Erythrocytes ]
- Cross reactivity against Carbonic Anhydrase I from other tissues and species may occur but have not been specifically determined
- Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide
- They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid
- They show extensive diversity in tissue distribution and in their subcellular localization
- CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes
- Variants of this gene have been described in some populations
- Multiple alternatively spliced variants, encoding the same protein, have been identified
- Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.