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7192810

CD5 Monoclonal Antibody (53-7.3), PE-eFluor™ 610, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD5

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

alanyl (membrane) aminopeptidase; alanyl aminopeptidase; alanyl aminopeptidase, membrane; aminopeptidase M; Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD antigen CD5; CD13; CD28; CD28 antigen (Tp44); CD28 molecule; Cd5; CD5 antigen; CD5 antigen (p56 62); CD5 antigen (p56-62); CD5 antigen p56-62; CD5 molecule; CD5 protein; CD74 antigen, invariant polypeptide of major; cell surface protein; costimulatory molecule B7 receptor CD28; fCD5; GP150; hAPN; LAP1; LEU1; Ly-1; Ly12; Ly-12; LyA; Ly-A; Lymphocyte antigen 1; Lymphocyte antigen CD5; lymphocyte antigen T1/Leu-1; Lyt-1; membrane alanyl aminopeptidase; microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; P150; Pan T cell; PEPN; T1; T-cell costimulatory molecule CD28; T-cell surface glycoprotein CD5; T-cell-specific surface glycoprotein CD28; unnamed protein product

Gene Symbols

Cd5

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

Cd5

Clone

53-7.3

Applications

Flow Cytometry

Conjugate

PE-eFluor 610

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P13379

Gene ID (Entrez)

12507

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Product Type

Antibody

Description

  • CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein
  • CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas
  • CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation
  • CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes
  • In lymph nodes, the main reactivity is observed in T cell areas
  • CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells
  • Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.