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7193099

CD5 Monoclonal Antibody (L17F12), Super Bright™ 436, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD5

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias

alanyl (membrane) aminopeptidase; alanyl aminopeptidase; alanyl aminopeptidase, membrane; aminopeptidase M; Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD antigen CD5; CD13; CD28; CD28 antigen (Tp44); CD28 molecule; Cd5; CD5 antigen; CD5 antigen (p56 62); CD5 antigen (p56-62); CD5 antigen p56-62; CD5 molecule; CD5 protein; CD74 antigen, invariant polypeptide of major; cell surface protein; costimulatory molecule B7 receptor CD28; fCD5; GP150; hAPN; LAP1; LEU1; Ly-1; Ly12; Ly-12; LyA; Ly-A; Lymphocyte antigen 1; Lymphocyte antigen CD5; lymphocyte antigen T1/Leu-1; Lyt-1; membrane alanyl aminopeptidase; microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; P150; Pan T cell; PEPN; T1; T-cell costimulatory molecule CD28; T-cell surface glycoprotein CD5; T-cell-specific surface glycoprotein CD28; unnamed protein product

Gene Symbols

Cd5

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

Cd5

Clone

L17F12

Applications

Flow Cytometry

Conjugate

Super Bright 436

Host Species

Mouse

Target Species

Human

Gene Accession No.

P06127

Gene ID (Entrez)

921

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Product Type

Antibody

Description

  • Mouse Monoclonal Antibody CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein
  • CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas
  • CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation
  • CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes
  • In lymph nodes, the main reactivity is observed in T cell areas
  • CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells
  • Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.