HRX Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 72-013-3-Each-of-1 | In Stock | ₹ 44,633.50 |
72-013-3 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,633.50
GST (18%): ₹ 8,034.03
Total Price: ₹ 52,667.53
Antigen
HRX
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KMT2A
Gene Alias
6430520K01; ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; histone-lysine N-methyltransferase 2A; histone-lysine N-methyltransferase MLL; HRX; HTRX; HTRX1; Kmt2a; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; lysine N-methyltransferase 2A; mixed lineage leukemia 1; mKIAA4050; Mll; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia 1; myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; trithorax Drosophila; trithorax-like protein; TRX1; WDSTS; zinc finger protein HRX
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4297
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration
0.5 mg/mL
Formulation
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q03164
Gene Symbols
KMT2A
Immunogen
Protein corresponding to Human KMT2A (aa 700-1000)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides
- The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide
- The purified antibody is tested for its functionality in various relevant research applications
- The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature
- This antibody is predicted to react with Monkey, Equine, Pig, Bovine, Rabbit, Rat and Mouse
- KMT2A is a histone methyltransferase that plays an essential role in early development and hematopoiesis
- It is a catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac)
- In the MLL1/MLL complex, KMT2A specifically mediates H3K4me, a tag for epigenetic transcriptional activation
- KMT2A has weak methyltransferase activity by itself, and requires other components of the MLL1/MLL complex to obtain full methyltransferase activity
- It has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', and has higher activity toward H3 acetylated on 'Lys-9'
- Required for transcriptional activation of HOXA9 and promotes PPP1R15A-induced apoptosis.