72-039-6

PKN1 Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 72-039-6-Each-of-1 In Stock ₹ 44,500.00

72-039-6 - Each of 1

₹ 44,500.00

In Stock

Quantity

1

Base Price: ₹ 44,500.00

GST (18%): ₹ 8,010.00

Total Price: ₹ 52,510.00

Antigen

PKN1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PKN1

Gene Alias

DBK; F730027O18Rik; PAK1; PAK-1; PKN; PKN1; PKN-ALPHA; PRK1; Prkcl1; Protease-activated kinase 1; protein kinase C-like 1; Protein kinase C-like PKN; protein kinase C-related kinase 1; protein kinase N1; protein kinase PKN; protein kinase PKN-alpha; Protein-kinase C-related kinase 1; serine/threonine kinase 3; serine/threonine protein kinase N; serine/threonine-protein kinase N1; serine-threonine kinase N; serine-threonine protein kinase N; Stk3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5585

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.

Q16512

Gene Symbols

PKN1

Immunogen

Peptides corresponding to human PKN1 [1) 4-22 2) aa922-aa939]

Quantity

100μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • This antibody is predicted to react with Monkey, Bovine, Dog
  • PKN1 (PRK1) belongs to the protein kinase C superfamily
  • This kinase is activated by the Rho family of small G proteins and may mediate the Rho-dependent signaling pathway
  • This kinase can also be activated by phospholipids
  • The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton
  • The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis
  • Alternatively spliced transcript variants encoding distinct isoforms have been observed.