7200879

Integrin alpha 4/CD49d Antibody (44H6) - BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Integrin alpha 4/CD49d

Concentration

1.0 mg/mL

Applications

Immunohistochemistry (Paraffin), Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Cancer, Cellular Markers, Cytoskeleton Markers

Gene Accession No.

P13612

Gene ID (Entrez)

3676

Immunogen

HOON pre-B leukemia cell line

Primary or Secondary

Primary

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Clone

44H6

Dilution

Flow Cytometry 1:40, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:50-1:100, Immunohistochemistry-Paraffin (Negative)

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human

Gene Alias

269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha

Gene Symbols

ITGA4

Isotype

IgG1

Purification Method

Protein A or G purified

Test Specificity

NB100-64903 recognizes CD49d, also known as Integrin alpha 4, which associates with either CD29 (integrin beta 1) or integrin beta 7. CD49d is a 150kD molecule, which may be cleaved to 80kD and 70kD fragments. It is expressed by lymphocytes, monocytes, eosinophils and thymocytes. VLA-4 mediates cell adhesion to VCAM-1 and fibronectin. 44H6 induces homotypic aggregation.

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Description

  • Description Integrin alpha 4/CD49d Monoclonal specifically detects Integrin alpha 4/CD49d in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin (Negative).