ER-HR3 Antibody (ER-HR3) - BSA Free

ER-HR3

1.0 mg/mL

Immunohistochemistry (Frozen), Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Flow Cytometry

Unconjugated

Rat

Mouse

Adherent F1 (CBAxBL) bone marrow stormal cells.

Primary

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

ER-HR3

Flow Cytometry 1:10-1:50, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Monoclonal

Purified

RUO

Hematopoiesis related macrophage

IgG2c

Protein G purified

NB100-64931 recognizes the murine antigen ER-HR3. ER-HR3 is a cell surface antigen which is expressed by Langerhans cells in epithelium, a subset of mature macrophages and dendritic cells that are located predominantly in haematopoietic and lymphoid organs. Initial studies of ER-HR3 demonstrated expression on peripheral blood monocytes but recent studies suggest that expression is actually very low. During foetal development, ER-HR3 positive cells are localised to haemapoietic islands and are often associated with erythroid progenitor cells. The functions of the ER-HR3 antigen have not been established but reports suggest that the antigen may be involved in adult erythropoiesis and in the regulation of the immune response. Clone ER-HR3 does not inhibit T cell proliferation in antigen-specific T-cell proliferation studies. Clone ER-HR3 recognizes two proteins of approximately 69kD and 55kD under non-reducing conditions.