Phospho-c-Fos (Ser32) Recombinant Rabbit Monoclonal Antibody (cFosS32-BA9), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Phospho-c-Fos (Ser32)
Concentration
0.5 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Alias
activator protein 1; AP-1; cellular oncogene c-fos; cellular oncogene fos; cFos; C-FOS; c-fos oncogene; c-fos protooncogene protein; D12Rfj1; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS); FBJ murine osteosarcoma viral oncogene homolog; FBJ murine osteosarcoma viral oncogene homolog B; FBJ osteosarcoma oncogene; FBJ osteosarcoma oncogene B; FBJ osteosarcoma viral oncogene isoform deltaFosb-2; FOS; Fos proto-oncogene, AP-1 trancription factor subunit; Fos proto-oncogene, AP-1 transcription factor subunit; Fosb; FosB proto-oncogene, AP-1 transcription factor subunit; fra-2; G0/G1 switch regulatory protein 7; G0S7; I79_009428; p55; protein fosB; proto-oncogene cFOS; proto-oncogene c-Fos; proto-oncogene protein c-fos; v-fos FBJ murine osteosarcoma viral oncogene homolog
Gene Symbols
FOS
Isotype
IgG κ
Purification Method
Protein A/G
Product Type
Antibody
Clone
cFosS32-BA9
Applications
Flow Cytometry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse, Rat
Gene Accession No.
P01100, P01101, P12841
Gene ID (Entrez)
14281, 2353, 314322
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser32 of human phospho c-Fos.
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
FOS
Related Products
Description
- FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos)
- It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14
- c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation
- c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites
- The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.