7226330

FGF23 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

FGF23

Applications

Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q9GZV9

Gene ID (Entrez)

8074

Immunogen

Phe157-Gly238 (Accession Q9GZV9)

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

FGF23

Concentration

0.5 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

ADHR; FGF; Fgf23; FGF-23; FGFN; Fibroblast growth factor; Fibroblast growth factor 23; Fibroblast growth factor 23 C-terminal peptide; Fibroblast growth factor 23 N-terminal peptide; HPDR2; HYPF; Phosphatonin; PHPTC; tumor-derived hypophosphatemia inducing factor; Tumor-derived hypophosphatemia-inducing factor; UNQ3027/PRO9828

Gene Symbols

FGF23

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • The protein encoded by this gene is a member of the fibroblast growth factor family
  • FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion
  • The product of this gene inhibits renal tubular phosphate transport
  • This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets, an inherited phosphate wasting disorder
  • Abnormally high level expression of this gene was found in oncogenic hypophosphatemic osteomalacia, a phenotypically similar disease caused by abnormal phosphate metabolism
  • Mutations in this gene have also been shown to cause familial tumoral calcinosis with hyperphosphatemia.