CXCL17 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CXCL17
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q6UXB2
Gene ID (Entrez)
284340
Immunogen
Leu24-Leu119 (Accession Q6UXB2), with N-terminal His and GST Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
CXCL17
Concentration
0.55 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
13.6 kDa protein; 13.6-kDa protein; 4-Cys CXCL17; 6-Cys CXCL17; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 17; CXC; CXC motif chemokine; C-X-C motif chemokine 17; C-X-C motif chemokine ligand 17; CXCL; CXCL17; Dcip1; Dendritic cell and monocyte chemokine-like protein; DMC; UNQ473; UNQ473/PRO842; Vcc1; VCC-1; VEGF coregulated chemokine 1; VEGF co-regulated chemokine 1
Gene Symbols
CXCL17
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- CXCL17 is a chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells
- In particular, CXCL17 is a mucosal chemokine that attracts dendritic cells and blood monocytes to the lungs
- CXCL17 plays a role in angiogenesis and possibly in the development of tumors
- Further, CXCL17 acts as an anti-inflammatory in the stomach and may play a role in the innate defense against infections
- CXCL17 also activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions
- 4-Cys CXCL17 seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17
- Diseases associated with CXCL17 dysfunction include cholera.