ABCC11 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
ABCC11
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q96J66
Gene ID (Entrez)
85320
Immunogen
Ile1141-Arg1382 (Accession Q96J66), with N-terminal His Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
ABCC11
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
ABCC11; ATP binding cassette subfamily C member 11; ATP-binding cassette protein C11; ATP-binding cassette sub-family C member 11; ATP-binding cassette transporter MRP8; ATP-binding cassette transporter sub-family C member 11; ATP-binding cassette, sub-family C (CFTR/MRP), member 11; EWWD; MRP8; multidrug resistance-associated protein 8; multi-resistance protein 8; WW
Gene Symbols
ABCC11
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters
- ABC proteins transport various molecules across extra- and intra-cellular membranes
- ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White)
- This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance
- The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides
- In addition, a SNP in this gene is responsible for determination of human earwax type
- This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1
- Multiple alternatively spliced transcript variants have been described for this gene.