7240480
Thrombopoietin Monoclonal Antibody (9H10H8D11), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Thrombopoietin
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
C-mpl ligand; Megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; megakaryocyte stimulating factor; Mgdf; MKCSF; ML; MPL ligand; Mpllg; MSA; Myeloproliferative leukemia virus oncogene ligand; prepro-thrombopoietin; TDH2A; THCYT1; THPO; Thrombopoietin; thyroid microsomal antigen; thyroid peroxidase; thyroperoxidase; Tpo; TPX
Gene Symbols
THPO
Isotype
IgG1
Purification Method
Protein A
Product Type
Antibody
Clone
9H10H8D11
Applications
ELISA
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P40225
Gene ID (Entrez)
7066
Immunogen
Human full-length cell-derived rhTHPO.
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Gene
THPO
Related Products
Description
- Specificity: Human THPO Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage
- Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, μgtimately, to the production of platelets (thrombopoiesis)
- Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.