7240810
CD138 (Syndecan-1) Monoclonal Antibody (C3), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD138 (Syndecan-1)
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
AA408134; AA409076; CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; HSPG; sCD138; SDC; Sdc1; soluble CD138; Sstn; syn-1; Synd; SYND1; Synd-1; SYNDECA; syndecan; syndecan 1; syndecan proteoglycan 1; Syndecan1; syndecan-1; synstatin
Gene Symbols
Sdc1
Isotype
IgG1 κ
Purification Method
Protein A/G
Product Type
Antibody
Clone
C3
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P18827
Gene ID (Entrez)
6382
Immunogen
Gln23-Leu253 (Accession P18827), with N-terminal His and GST Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
Sdc1
Related Products
Description
- CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes
- CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury
- It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells
- Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics
- Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.