7240966

IL-18 Monoclonal Antibody (C10), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

IL-18

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

cytokine; iboctadekin; IFN-gamma-inducing factor; IGIF; il 18; IL-1 gamma; IL18; IL-18; IL1F4; IL-1g; ILN; interferon gamma inducing factor; interferon gamma-inducing factor; interferon-gamma-inducing factor; Interleukin; interleukin 18; interleukin 18 (interferon-gamma-inducing factor); interleukin-1 gamma; Interleukin18; Interleukin-18; interleukin-18 proprotein; interleukin-18-like protein; MGC12320

Gene Symbols

IL18

Isotype

IgG2b κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

C10

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Porcine, Rat

Gene Accession No.

O19073, P97636, Q14116

Gene ID (Entrez)

29197, 3606, 397057

Immunogen

Arg94-Asp193 (Accession Q14116), with N-terminal His Tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

IL18

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Description

  • The protein encoded by this gene is a proinflammatory cytokine
  • This cytokine can induce the IFN-gamma production of T cells
  • The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells
  • IL-18 binding protein can specifically interact with this cytokine, and thus negatively regulate its biological activity.