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75-501-9682

CD11b Monoclonal Antibody (C67F154), Alexa Fluor™ Plus 594, Invitrogen™

Manufacturer: LIFE TECHNOLOGIES

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Pack Size SKU Availability Price
Each of 1 75-501-9682-Each-of-1 In Stock ₹ 44,055.00

75-501-9682 - Each of 1

₹ 44,055.00

In Stock

Quantity

1

Base Price: ₹ 44,055.00

GST (18%): ₹ 7,929.90

Total Price: ₹ 51,984.90

Antigen

CD11b

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.5% BSA, 10% proprietary stabilizer and 0.05% sodium azide; pH 7.2

Gene Accession No.

P11215

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3684

Content And Storage

4° C, store in dark

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Clone

C67F154

Conjugate

Alexa Fluor Plus 594

Gene

ITGAM

Gene Alias

antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product

Immunogen

E. coli fragment of part of extracellular domain (aa 250-350)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Description

  • Description: The C67F154 monoclonal antibody reacts with human CD11b
  • CD11b, also known as integrin alpha-M, is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18)
  • The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1 (macrophage-1 antigen), and CR3 (complement receptor 3)
  • CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain
  • CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X
  • These adhesions are critical for cell-cell and cell-matrix interactions
  • Applications Reported: This C67F154 antibody has been reported for use in immunohistochemistry and western blotting
  • Applications Tested: This C67F154 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded tissue using high pH antigen retrieval and can be used at 20 μg/mL
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Using conjugate solutions: Centrifuge the protein conjugate solution briefly in a microcentrifuge before use; add only the supernatant to the experiment
  • This step will help eliminate any protein aggregates that may have formed during storage, thereby reducing nonspecific background staining
  • CD11b Monoclonal antibody specifically detects CD11b in Human samples
  • It is validated for Immunohistochemistry (Paraffin)