89-000-591

crystallin, gamma C, Mouse, Clone: 7C4, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-000-591-Each-of-1 In Stock ₹ 52,421.00

89-000-591 - Each of 1

₹ 52,421.00

In Stock

Quantity

1

Base Price: ₹ 52,421.00

GST (18%): ₹ 9,435.78

Total Price: ₹ 61,856.78

Antigen

crystallin, gamma C

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_020989

Gene Symbols

CRYGC

Immunogen

CRYGC (NP_066269, 75 a.a. ∼ 174 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Whole Molecule

Yes

Gene ID (Entrez)

1420

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2a κ

Applications

ELISA, Western Blot

Clone

7C4

Description

Mouse monoclonal antibody raised against a partial recombinant CRYGC.

Gene

CRYGC

Gene Alias

CCL/CRYG3

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

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Description

  • Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous
  • The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens
  • Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins
  • Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily
  • Alpha and beta families are further divided into acidic and basic groups
  • Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions
  • Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions
  • They are differentially regulated after early development
  • Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster
  • Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation
  • [provided by RefSeq Sequence: SIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY