89-000-597
cystatin B (stefin B), Mouse, Clone: M2-F1, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-000-597-Each-of-1 | In Stock | ₹ 42,898.00 |
89-000-597 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,898.00
GST (18%): ₹ 7,721.64
Total Price: ₹ 50,619.64
Antigen
cystatin B (stefin B)
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
BC003370.1
Gene Symbols
CSTB
Immunogen
CSTB (AAH03370.1, 1 a.a. ∼ 98 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Whole Molecule
Yes
Gene ID (Entrez)
1476
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1 κ
Applications
ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Clone
M2-F1
Description
Mouse monoclonal antibody raised against a full length recombinant CSTB.
Gene
CSTB
Gene Alias
CST6/EPM1/PME/STFB
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Related Products
Description
- The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences
- Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity
- There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens
- This gene encodes a stefin that functions as an intracellular thiol protease inhibitor
- The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b
- The protein is thought to play a role in protecting against the proteases leaking from lysosomes
- Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1)
- [provided by RefSeq Sequence: MMCGAPSATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF