89-000-903

mitogen-activated protein kinase 10, Mouse, Clone: 3A3-1A8, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-000-903-Each-of-1 In Stock ₹ 42,898.00

89-000-903 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

mitogen-activated protein kinase 10

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

BC065516

Gene Symbols

MAPK10

Immunogen

MAPK10 (AAH65516.1, 1 a.a. ∼ 319 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Research Discipline

Kinases

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA, Western Blot

Clone

3A3-1A8

Description

Mouse monoclonal antibody raised against a full length recombinant MAPK10.

Gene

MAPK10

Gene Alias

FLJ12099/FLJ33785/JNK3/JNK3A/MGC50974/PRKM10/p493F12/p54bSAPK

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Whole Molecule

Yes

Gene ID (Entrez)

5602

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1 κ

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Description

  • The protein encoded by this gene is a member of the MAP kinase family
  • MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development
  • This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs)
  • Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis
  • Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4)
  • Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis
  • Four alternatively spliced transcript variants encoding distinct isoforms have been reported
  • [provided by RefSeq Sequence: MELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR