89-000-946

ribosomal protein S6 kinase, 70kDa, polypeptide 1, Mouse, Clone: 1E10, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-000-946-Each-of-1 In Stock ₹ 47,793.00

89-000-946 - Each of 1

₹ 47,793.00

In Stock

Quantity

1

Base Price: ₹ 47,793.00

GST (18%): ₹ 8,602.74

Total Price: ₹ 56,395.74

Antigen

ribosomal protein S6 kinase, 70kDa, polypeptide 1

Classification

Cocktail

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_003161

Gene Symbols

RPS6KB1

Immunogen

RPS6KB1 (NP_003152, 416 a.a. ∼ 525 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Research Discipline

Kinases

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA, Immunofluorescence, In situ PLA, Western Blot

Clone

1E10

Description

Mouse monoclonal antibody raised against a partial recombinant RPS6KB1.

Gene

RPS6KB1

Gene Alias

PS6K/S6K/S6K1/STK14A/p70(S6K)-alpha/p70-S6K/p70-alpha

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Whole Molecule

Yes

Gene ID (Entrez)

6198

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

Ig Mix

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Description

  • This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases
  • This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein
  • The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation
  • Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines
  • Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized
  • [provided by RefSeq Sequence: PSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL