89-001-009

TEK tyrosine kinase, endothelial, Mouse, Clone: 1A4, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-001-009-Each-of-1 In Stock ₹ 42,898.00

89-001-009 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

TEK tyrosine kinase, endothelial

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

BC035514

Gene Symbols

TEK

Immunogen

TEK (AAH35514, 701 a.a. ∼ 800 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Research Discipline

Kinases

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA, Western Blot

Clone

1A4

Description

Mouse monoclonal antibody raised against a partial recombinant TEK.

Gene

TEK

Gene Alias

CD202B/TIE-2/TIE2/VMCM/VMCM1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Whole Molecule

Yes

Gene ID (Entrez)

7010

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2a κ

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Description

  • The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans
  • This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats
  • The ligand for the receptor is angiopoietin-1
  • Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis
  • TEK is closely related to the TIE receptor tyrosine kinase
  • [provided by RefSeq Sequence: AFSHELVTLPESQAPADLGGGKMLLIAILGSAGMTCLTVLLAFLIILQLKRANVQRRMAQAFQNVREEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWND