89-001-136

mitogen-activated protein kinase kinase kinase kinase 4, Mouse, Clone: 4A5, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-001-136-Each-of-1 In Stock ₹ 42,898.00

89-001-136 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

mitogen-activated protein kinase kinase kinase kinase 4

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_145686

Gene Symbols

MAP4K4

Immunogen

MAP4K4 (NP_663719, 611 a.a. ∼ 710 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Research Discipline

Kinases

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA, Immunohistochemistry (PFA fixed), Western Blot

Clone

4A5

Description

Mouse monoclonal antibody raised against a partial recombinant MAP4K4.

Gene

MAP4K4

Gene Alias

FLH21957/FLJ10410/FLJ20373/FLJ90111/HGK/KIAA0687/NIK

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Whole Molecule

Yes

Gene ID (Entrez)

9448

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1 κ

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Description

  • The protein encoded by this gene is a member of the serine/threonine protein kinase family
  • This kinase has been shown to specifically activate MAPK8/JNK
  • The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway
  • Alternatively spliced transcript variants encoding different isoforms have been identified
  • [provided by RefSeq Sequence: VHPALQRPAEPQVQWSHLASLKNNVSPVSRSHSFSDPSPKFAHHHLRSQDPCPPSRSEVLSQSSDSKSEAPDPTQKAWSRSDSDEVPPRVPVRTTSRSPV