89-005-537
HLA-DQB1, Mouse, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-005-537-Each-of-1 | In Stock | ₹ 42,898.00 |
89-005-537 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,898.00
GST (18%): ₹ 7,721.64
Total Price: ₹ 50,619.64
Antigen
HLA-DQB1
Classification
Polyclonal
Description
Mouse polyclonal antibody raised against a full-length human HLA-DQB1 protein.
Gene
HLA-DQB1
Gene Alias
CELIAC1/HLA-DQB/IDDM1
Host Species
Mouse
Quantity
50 μL
Whole Molecule
Yes
Gene ID (Entrez)
3119
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Applications
Flow Cytometry, Western Blot
Conjugate
Unconjugated
Formulation
No additive
Gene Accession No.
BC012106
Gene Symbols
HLA-DQB1
Immunogen
HLA-DQB1 (AAH12106, 1 a.a. ∼ 261 a.a) full-length human protein.
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Serum
Related Products
Description
- HLA-DQB1 belongs to the HLA class II beta chain paralogues
- This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane
- It plays a central role in the immune system by presenting peptides derived from extracellular proteins
- Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages)
- The beta chain is approximately 26-28kDa and it contains 6 exons
- Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail
- Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules
- Typing for these polymorphisms is routinely done for bone marrow transplantation
- [provided by RefSeq Sequence: MSWKKALRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKGLLH