mitogen-activated protein kinase 14, Mouse, Clone: 3D5, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-014-082-Each-of-1 | In Stock | ₹ 45,657.00 |
89-014-082 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,657.00
GST (18%): ₹ 8,218.26
Total Price: ₹ 53,875.26
Antigen
mitogen-activated protein kinase 14
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
BC031574
Gene Symbols
MAPK14
Immunogen
MAPK14 (AAH31574, 260 a.a. ∼ 360 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Research Discipline
Kinases
Gene ID (Entrez)
1432
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1 κ
Applications
ELISA, Immunohistochemistry (PFA fixed), Immunoprecipitation, In situ PLA, Western Blot
Clone
3D5
Description
Mouse monoclonal antibody raised against a partial recombinant MAPK14.
Gene
MAPK14
Gene Alias
CSBP1/CSBP2/CSPB1/EXIP/Mxi2/PRKM14/PRKM15/RK/SAPK2A/p38/p38ALPHA
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Related Products
Description
- The protein encoded by this gene is a member of the MAP kinase family
- MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development
- This kinase is activated by various environmental stresses and proinflammatory cytokines
- The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase
- The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response
- Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported
- [provided by RefSeq Sequence: QSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES