89-014-098

E2F transcription factor 3, Mouse, Clone: 5F7, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-014-098-Each-of-1 In Stock ₹ 42,898.00

89-014-098 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

E2F transcription factor 3

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_001949

Gene Symbols

E2F3

Immunogen

E2F3 (NP_001940, 336 a.a. ∼ 425 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Research Discipline

Cell Cycle

Gene ID (Entrez)

1871

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1 κ

Applications

ELISA, In situ PLA, Western Blot

Clone

5F7

Description

Mouse monoclonal antibody raised against a partial recombinant E2F3.

Gene

E2F3

Gene Alias

DKFZp686C18211/E2F-3/KIAA0075/MGC104598

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

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Description

  • The protein encoded by this gene is a member of the E2F family of transcription factors
  • The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses
  • The E2F proteins contain several evolutionally conserved domains found in most members of the family
  • These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain
  • This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain
  • This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner
  • [provided by RefSeq Sequence: QIHLASTQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEGPFVNL