89-014-221
breast cancer anti-estrogen resistance 3, Mouse, Clone: 3G4, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-014-221-Each-of-1 | In Stock | ₹ 42,898.00 |
89-014-221 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,898.00
GST (18%): ₹ 7,721.64
Total Price: ₹ 50,619.64
Antigen
breast cancer anti-estrogen resistance 3
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
BC039895
Gene Symbols
BCAR3
Immunogen
BCAR3 (AAH39895, 266 a.a. ∼ 373 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Research Discipline
Cell Cycle
Gene ID (Entrez)
8412
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG2a κ
Applications
ELISA, Western Blot
Clone
3G4
Description
Mouse monoclonal antibody raised against a partial recombinant BCAR3.
Gene
BCAR3
Gene Alias
KIAA0554/NSP2/SH2D3B
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Related Products
Description
- Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen
- However, breast cancers progress to become anti-estrogen resistant
- Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance
- The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells
- The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48
- [provided by RefSeq Sequence: YGTSPGQAREGSLTKGRPDVAKRLSLTMGGVQAREQNLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGCKLPPQSSGVDTSPCPNSPVFRTGSEPA