89-015-826

dihydropyrimidine dehydrogenase, Mouse, Clone: 7D4, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-015-826-Each-of-1 In Stock ₹ 42,898.00

89-015-826 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

dihydropyrimidine dehydrogenase

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_000110

Gene Symbols

DPYD

Immunogen

DPYD (NP_000101, 1 a.a. ∼ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA, Immunofluorescence, Western Blot

Clone

7D4

Description

Mouse monoclonal antibody raised against a partial recombinant DPYD.

Gene

DPYD

Gene Alias

DHP/DHPDHASE/DPD/MGC132008/MGC70799

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Gene ID (Entrez)

1806

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1 κ

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Description

  • The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism
  • Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy
  • Two transcript variants encoding different isoforms have been found for this gene
  • [provided by RefSeq Sequence: MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYY