89-015-853
hemochromatosis type 2 (juvenile), Mouse, Clone: 1C12, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-015-853-Each-of-1 | In Stock | ₹ 42,898.00 |
89-015-853 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,898.00
GST (18%): ₹ 7,721.64
Total Price: ₹ 50,619.64
Antigen
hemochromatosis type 2 (juvenile)
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
NM_202004
Gene Symbols
HFE2
Immunogen
HFE2 (NP_973733, 93 a.a. ∼ 173 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Applications
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Clone
1C12
Description
Mouse monoclonal antibody raised against a partial recombinant HFE2.
Gene
HFE2
Gene Alias
HFE2A/HJV/JH/MGC23953/RGMC
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Gene ID (Entrez)
148738
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG2a κ
Related Products
Description
- The product of this gene is involved in iron metabolism
- It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression
- It could also represent the cellular receptor for hepcidin
- Alternatively spliced transcript variants encoding different isoforms have been identified for this gene
- Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH)
- JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30
- [provided by RefSeq Sequence: GGCPPSQRLSRSERNRRGAITIDTARRLCKEGLPVEDAYFHSCVFDVLISGDPNFTVAAQAALEDARAFLPDLEKLHLFPS