89-016-607

F-box protein 32, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-016-607-Each-of-1 In Stock ₹ 46,458.00

89-016-607 - Each of 1

₹ 46,458.00

In Stock

Quantity

1

Base Price: ₹ 46,458.00

GST (18%): ₹ 8,362.44

Total Price: ₹ 54,820.44

Antigen

F-box protein 32

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a full-length human FBXO32 protein.

Gene

FBXO32

Gene Alias

FLJ32424/Fbx32/MAFbx/MGC33610

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

Western Blot

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_058229.2

Gene Symbols

FBXO32

Immunogen

FBXO32 (ENSP00000287396, 1 a.a. ∼ 355 a.a) full-length human protein.

Quantity

50 μg

Research Discipline

Ubiquitin/Proteasome

Gene ID (Entrez)

114907

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

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Description

  • This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box
  • The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination
  • The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs
  • The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain
  • This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy
  • This protein is thus a potential drug target for the treatment of muscle atrophy
  • Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes
  • [provided by RefSeq] Sequence: MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYNKENLFNSLNYDVAAKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKLVRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF