89-016-807

glutathione S-transferase mu 4, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-016-807-Each-of-1 In Stock ₹ 46,458.00

89-016-807 - Each of 1

₹ 46,458.00

In Stock

Quantity

1

Base Price: ₹ 46,458.00

GST (18%): ₹ 8,362.44

Total Price: ₹ 54,820.44

Antigen

glutathione S-transferase mu 4

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a full-length human GSTM4 protein.

Gene

GSTM4

Gene Alias

GSTM4-4/GTM4/MGC131945/MGC9247

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Gene ID (Entrez)

2948

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_000850.3

Gene Symbols

GSTM4

Immunogen

GSTM4 (NP_000841.1, 1 a.a. ∼ 218 a.a) full-length human protein.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

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Description

  • Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families
  • At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta
  • This gene encodes a glutathione S-transferase that belongs to the mu class
  • The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione
  • The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic
  • These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs
  • Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds
  • Multiple transcript variants, each encoding a distinct protein isoform, have been identified
  • [provided by RefSeq] Sequence: MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK