89-016-816

major histocompatibility complex, class II, DP alpha 1, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-016-816-Each-of-1 In Stock ₹ 49,484.00

89-016-816 - Each of 1

₹ 49,484.00

In Stock

Quantity

1

Base Price: ₹ 49,484.00

GST (18%): ₹ 8,907.12

Total Price: ₹ 58,391.12

Antigen

major histocompatibility complex, class II, DP alpha 1

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a full-length human HLA-DPA1 protein.

Gene

HLA-DPA1

Gene Alias

HLA-DP1A/HLADP/HLASB

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

Western Blot

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

BC009956

Gene Symbols

HLA-DPA1

Immunogen

HLA-DPA1 (AAH09956.1, 1 a.a. ∼ 260 a.a) full-length human protein.

Quantity

50 μg

Research Discipline

Membrane Receptors

Gene ID (Entrez)

3113

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

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Description

  • HLA-DPA1 belongs to the HLA class II alpha chain paralogues
  • This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane
  • It plays a central role in the immune system by presenting peptides derived from extracellular proteins
  • Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages)
  • The alpha chain is approximately 33-35kDa and its gene contains 5 exons
  • Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail
  • Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules
  • [provided by RefSeq Sequence: MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDEDEQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTLIQRSNHTQAANDPPEVTVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLPRTDYSFHKFHYLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLRSGHDPRAQGPL