89-018-392
legumain, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-018-392-Each-of-1 | In Stock | ₹ 49,662.00 |
89-018-392 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,662.00
GST (18%): ₹ 8,939.16
Total Price: ₹ 58,601.16
Antigen
legumain
Classification
Polyclonal
Description
Rabbit polyclonal antibody raised against a full-length human LGMN protein.
Gene
LGMN
Gene Alias
AEP/LGMN1/PRSC1
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Applications
Western Blot
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
NM_001008530.1
Gene Symbols
LGMN
Immunogen
LGMN (NP_001008530.1, 1 a.a. ∼ 433 a.a) full-length human protein.
Quantity
100 μg
Research Discipline
Kinases
Gene ID (Entrez)
5641
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG
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Description
- This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds
- This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems
- Enzyme activation is triggered by acidic pH and appears to be autocatalytic
- Protein expression occurs after monocytes differentiate into dendritic cells
- A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells
- Overexpression of this gene may be associated with the majority of solid tumor types
- This gene has a pseudogene on chromosome 13
- Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined
- These two variants encode the same isoform
- [provided by RefSeq Sequence: MVWKVAVFLSVALGIGAVPIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPDVPLTIMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY