89-021-134
COMT, Mouse, Clone: 1G4-1A1, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-021-134-Each-of-1 | In Stock | ₹ 42,898.00 |
89-021-134 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,898.00
GST (18%): ₹ 7,721.64
Total Price: ₹ 50,619.64
Antigen
COMT
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
BC000419
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1312
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form
Liquid
Applications
ELISA, Western Blot
Clone
1G4-1A1
Description
Mouse monoclonal antibody raised against a full length recombinant COMT.
Gene
COMT
Gene Symbols
COMT
Immunogen
COMT (AAH00419.2, 1 a.a. ∼ 182 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine
- This O-methylation results in one of the major degradative pathways of the catecholamine transmitters
- In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease
- COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT)
- The differences between S-COMT and MB-COMT reside within the N-termini
- Several transcript variants are formed through the use of alternative translation initiation sites and promoters
- [provided by RefSeq Sequence: MNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGMKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP