89-021-255
DAG1, Mouse, Clone: 2A3, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-021-255-Each-of-1 | In Stock | ₹ 40,851.00 |
89-021-255 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,851.00
GST (18%): ₹ 7,353.18
Total Price: ₹ 48,204.18
Antigen
DAG1
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
BC012740
Gene Symbols
DAG1
Immunogen
DAG1 (AAH12740, 31 a.a. ∼ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Applications
ELISA, Western Blot
Clone
2A3
Description
Mouse monoclonal antibody raised against a partial recombinant DAG1.
Gene
DAG1
Gene Alias
156DAG/A3a/AGRNR/DAG
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1605
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form
Liquid
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Description
- Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix
- Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies
- The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis
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- The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence
- Alternative splicing results in multiple transcript variants Sequence: WPSEPSEAVRDWENQLEASMHSVLSDLHEAVPTVVGIPDGTAVVGRSFRVTIPTDLIASSGDIIKVSAAGKEALPSWLHWDSQSHTLEGLPLDTDKGVHYISVSATRLGA